What effect does nicotine have on blood vessels?

Nicotine has a significant effect on blood vessels, primarily causing contraction and potentially leading to a weakening of the vessel structure over time. When nicotine enters the bloodstream, it stimulates the release of catecholamines, such as adrenaline, which can constrict blood vessels. This contraction reduces blood flow to various tissues and can increase blood pressure. Chronic exposure to nicotine can also lead to damage of the blood vessel walls, contributing to conditions such as atherosclerosis. This process can ultimately weaken the blood vessels, making them less elastic and more prone to injury. Understanding this effect is crucial, especially in terms of how nicotine impacts cardiovascular health and overall skin physiology.